The combination of planets representing the nativity defeating others

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In the Matheosis Libri VIII, it seems that benefic planets (like Jupiter) in the 12th house results in strong enemies and enemies' defeating the nativity, and weaker malefic planets may lead to the winning of the nativity over his/her enemies. I wonder if that's true and what kind of combination of planets can endow the nativity with the glory of victory over enemies/competitors. And if the above is right, what influences can it has on the nativity's competition when the weak malefic planets in the 12th house/as the ruler of the 12th house relates to the lord of the ascendant (e.g. mutual reception, in conjunction, or the same planet (rising Aquarius) etc.)?