The profection is in the 2nd whole sign, Cancer, with the Moon in the profected 11th conjunct the 12th.

Event: August 6, 1844 Birth of Prince Alfred
On August 6, 1844 Victoria gave birth to her second son, Prince Alfred. She was 25 years old; the profection was in the 2nd. The Age Arc was 25º 12'.

• the directed 2nd is critical (Profection is in 2nd sign). The radix 2nd is in Gemini, which is on the 12th (confinement)
• the directed Moon (LoY, domestic concerns) is changing degree, moving from a sextile of the Sun (ruler of radix 5th) to a mitigated semi-sextile (conj) with the lot of Children, female which is itself changing degree, turning critical
• the other lot of Children, female is also changing degree, moving to conjunct the Sun (male)
• in the maiora esse, Uranus is critical in the profected 6th (illness, injury)
• in the minora esse, Saturn (male) is critical along with the lot of Children in a woman's chart

The active planets (other than the Moon) are male and the Sun rules the lot of Children in a woman's chart.

Edit: See a revised analysis under Victoria - Profected 2nd - Custom Cusps

The profection is in the 3rd whole sign, Leo, with the Sun in the 10th.

Event: August 6, 1845 – Travels to Belgium and Germany
On August 6, 1845 the Queen travelled to Belgium and then on to Germany and Prince Albert's birthplace. She was 26 years old, the Age Arc was 26º 12'.

• the directed 2nd is moving out of a critical degree
• the directed Moon, a general significator of travel and ruler of the radix 3rd, is critical while the in a profected 3rd (travel) year
• directed Mars is critical and semi-sextile the directed lot of Journeys while in the profected 9th (foreign travel)
• the directed Asc is changing degree, moving to sextile the directed North Node (critical event)
• the directed Sun (in the profected 10th) is changing degree, moving from a conjunction with the SAN (status)
• in the maiora esse, Uranus is still critical; the Asc is sextile the directed Sun; the lot of Travel is trine Neptune (part of the trip was by water) and the lot of Journeys is conjunct Pluto (state visit?)
• in the minora esse, Jupiter is critical at 0 TA, the Asc is conjunct the South Node, the Moon is trine radix Mars, Saturn is sextile the directed Sun and the lot of Journeys is conjunct the radix Asc

The profection is in the 4th whole sign, Virgo, intercepted in the radix 5th. Mercury is in the profected 9th, radix 12th.

Event: May 25, 1846 – Birth of Princess Helena
On May 25, 1846 Victoria gave birth to her 5th child and 3rd daughter, Princess Helena. She was 27 years old. The Age Arc was 27º 00'.

• the directed lot of Children, female is critical in Gemini, ruled by Mercury (LoY) while the directed Asc is changing degrees, moving into the square of the lots radix counterpart and, at the same time, moving to conjunct radix Mars in the 12th (profected 8th)
• the directed MC is changing degree, moving into the sextile of directed Venus (girl) and semi-sextile (mitigated conj) directed Jupiter (children); in the radix its in Aquarius which is on the profected 6th and contains Jupiter
• the directed 12th is changing degree, moving to semi-sextile directed Mercury (LoY); in the radix it is in Aries which is on the profected 8th
• the directed 2nd is changing degree, moving with the directed Moon, the two are maintaining a mitigated sextile (trine) with the Moon moving to conjunct radix Pluto
• the directed Sun, ruler of the radix 4th (end of matter) and 5th (children) is changing degree, moving out of a conjunction with the directed SAN
• in the maiora esse, the lot of Children, female was critical, reinforcing its radix and directed counterparts which were also critical
• in the minora esse, the other, Dorothean lot of Children, female, was critical

There's a lot going on here, not all pleasant; checking the web, found that Helena's birth was a difficult one for Victoria. Wikipedia quotes a letter from Prince Albert to his brother shortly after her birth saying she was “born quite blue” and that Victoria “suffered longer and more than the other times and she will have to remain very quiet to recover.”

The profection is in the 5th whole sign, Libra, with Venus in profected 7th and ruling the profected 1st and 8th; radix 6th, co-rules the 12th where Taurus is intercepted.

Event: March 3, 1848 – Birth of a Daughter
On March 3, 1848 Victoria gave birth to her 6th child, and 4th daughter, Princess Louise. She was 28 years old. The Age Arc was 28º 46'.

• the directed lot of Children, male was critical but not involved in a directed aspect, nor was Mercury, its ruler
• the directed Asc was changing degree but it was not involved in a directed aspect; its ruler, Mars, was also changing degree, moving from a sextile of radix Venus to an inconjunct of the directed lot of Children in a woman's chart
• the directed Sun, ruler of the radix 5th, profected 12th, was changing degree, moving to trine directed Uranus (for the first time, Victoria was given chloroform during the birth) and while conjunct the directed SAN
• the directed Moon was changing degree, moving to semi-sextile the lot of Children, female and sextile (mitigated to a trine) radix Uranus
• directed Mars was changing degree, moving to inconjunct the directed lot of Children in a woman's chart
• Venus, the Lord of the Year, was square the radix Moon
• in the maiora esse, the Asc and the lot of Fortune (body) were critical
• in the minora esse, Mars, Jupiter, and the lot of Children were critical

The profection is in the 6th whole sign, Scorpio, intercepted in the 6th house. Mars is Lord of the Year; he is in, and rules, the profected 6th as well as the profected 1st.

Event: October 9, 1848 – Yacht crashes, 3 women drown

On October 9, 1848, while travelling from Osborne to Portsmouth aboard her yacht, the Fairy, it crashed into another boat, 3 woman drown; the Queen was 'haunted' by the tragedy. The Age Arc is 29º 23'

• the directed 2nd is changing degrees, moving from the sextile of directed Mars (LoY) who is not involved in a directed aspect. The radix 2nd is in Gemini which is on the profected 8th
• directed Jupiter (ruler of the radix 8th) is changing degree, moving from a mitigated semi-sextile (conj) with the directed MC, and a semi-sextile with the directed lot of Violence, to the trine of the radix Moon
• in the maiora esse, Mars (LoY) and the North Node are both critical and the Asc is sextile radix Mars while Uranus is sextile the directed lot of Violence and the lot of Death is in the square of directed Jupiter and the lot of Journey by Water is trine directed Jupiter
• in the minora esse, the Asc is sextile radix Uranus, Jupiter is trine the lot of Violence, and Mars (LoY) is in a mitigated square (double in power) with the radix Asc

On December 28, 1848 the first of many Christmas dramatic presentations, The Merchant of Venice, were performed at Windsor Castle. The profection is still in the 6th. The Age Arc was 29º 36'.

• no element is critical at any level of direction
• the directed Asc is changing degrees, moving to trine directed Neptune (illusion, drama)
• directed Mercury (ruler of the radix Asc) is changing degree, moving from a semi-sextile of directed Saturn to a semi-sextile of radix Jupiter, ruler of the profected 5th (children, pleasures)
• the directed SAN is changing degree, moving from a conjunction of the directed Sun and sextile of the radix Asc to a square of the directed MC (a public appearance?)

On May 19, 1949 Irishman William Adare fired a blank at her when she was returning from a drive; he was sentenced to 7 years transportation. The Age Arc was 29º 59'.

• the directed lot of Death is critical but it is not involved in a directed aspect nor is its ruler, Venus (there had been two deaths earlier in the year, her Aunt Sophia and Lord Melbourne whom she considered a friend; the directed 11th is lying on a square of the lot)
• directed Uranus is changing degree while moving to oppose the radix Ascendant and the directed Asc is in the trine of directed Neptune, square the directed lot of Assassination and sextile the lot of Debilitated Bodies
• directed Pluto is changing degree, moving out of a square with the directed lot of the Critical Year
• the directed Sun is conjunct the directed SAN
• directed Saturn is sextile radix Mars
• the lot of the Destroyer is critical in both the maiora and minora esse

The profection was in the 7th, Sagittarius, with Jupiter in the profected 3rd and ruling the profected 1st and 4th.

Event: October 30, 1849-Victoria confined to home with chicken-pox
On October 30, 1849 Victoria had to forego public appearances, being kept at home with a case of the chicken-pox. The Age Arc was 30º 26'.

• directed Venus, ruler of the profected 6th (illness) is critical, inconjunct (mitigated to an opposition by being in antiscion signs) the directed Dorothean lot of Death, and trine the radix lot of the Destroyer, both of which are also critical
• the directed Asc is changing degrees, moving out of the trine of directed Neptune, the sextile of the directed lot of Debilitated Bodies, and the trine of the Olympiodorus radix lot of Death while the radix Asc is in the trine of directed Uranus
• directed Pluto is changing degree, moving into a mitigated semi-sextile (conjunction) with radix Mars in the radix 12th, profected 5th (childhood disease?) with Mars ruling the lot of Fortune (body) which is also changing degree but not actively involved in a direction
• the directed SAN is changing degree, moving from the sextile of the radix Moon to the sextile radix Sun (these always move together, everything that affects her body (Moon) also affects her status (Sun) and position in life (SAN))
• in the maiora esse Mars (in the radix 12th), Jupiter (LoY) and the lot of Debilitated Bodies (by direction sextile directed Asc) are critical
• in the minora esse, nothing is critical; the Asc is within 1º of an opposition with the directed lot of Illness

There are no harsh directed aspects involving the malefics so its unlikely her life was in any danger from the illness and Jupiter (LoY and ruler of the radix 8th) was cadent in the 3rd in the profected chart (she was stopped from travelling) and connected to the Moon (ruler of the profected 8th) in the profected 6th, by trine.

A curious little piece of history popped up when I was looking at this time in Victoria's life; apparently we have her to thank for today's chicken industry! See A Brief History of the Brief History of Hen Fever and Fancy Fowl: How an Evil Sea Captain and a Beloved Queen Made the World Crave KFC.

On December 2nd, 1849 Queen Alexandria, the wife of King William IV, died; she had always treated Victoria with “motherly affection.” The Age Arc was 30º 32'.

• directed Venus, ruler of the profected 6th (injury) and 11th (friends), is critical and inconjunct (mitigated to an opposition by being in antiscion signs) the Dorothean directed lot of Death
• the directed 3rd is changing degrees, moving out of the trine of directed Saturn and into the square of directed Mercury in the profected 6th (8th from the 11th of friends); the 3rd signifies relatives and the 6th (being the 3rd from the 4th of parents) signifies aunts and uncles (Queen Alexandria was her aunt by marriage)
• the directed Sun is changing degree, moving to sextile directed Jupiter (LoY in the 3rd)
• in the maiora esse, the 3rd is critical and Uranus is square the directed Asc and Mars is conjunct the directed IC
• in the minora esse, Mars and the North Node are critical with the Asc trine radix Mars and square radix Pluto

On May 1, 1850 Victoria gave birth to her 3rd son, Prince Arthur. The Age Arc was 30º 56'.

• directed Venus is critical and in opposition to the directed Dorothean lot of Children, Male
• the directed 2nd is changing degree, moving from an inconjunct of radix Uranus and to a mitigated (doubled in power) square of directed Mars
• the directed Sun is changing degree, moving out of a sextile with directed Jupiter conjunct radix MC
• directed Pluto is changing degree, moving out of a mitigated semi-sextile (conjunction) with radix Mars and trine with the radix lot of Children to semi-sextile radix Jupiter (LoY)
• the directed North Node is changing degree, moving into a mitigated sextile (trine) of directed Neptune
• in the maiora esse the MC, the Sun and the SAN are all critical and in trine aspect
• in the minora esse Mars and lot of Children are critical as is the North Node

Capricorn is on the profected Asc with Saturn is with Pluto in the profected 3rd and rules the profected 1st and 2nd.

Event: May 27, 1850 – Physically attacked
On May 27, 1850 Robert Pate, a retired officer, hit Victoria on the head with a cane as she was ending a visit to an ill family member in Piccadilly; he was sentenced to 7 years transportation. The Age Arc was 31º 0'.

• directed Venus, ruler of the radix 6th, is critical but not involved in a directed aspect
• the directed lot of Death is critical while the radix lot is in the trine of directed Mars
• the directed lot of Violence is moving out of a semi-sextile with the directed Sun and into a critical degree while the radix lot is in a mitigated square (doubled in power) with directed Neptune
• directed Mercury is changing degree, moving to sextile the directed lot of Travel
• directed Saturn (LoY) is changing degree, moving out of a semi-sextile with directed Pluto and a sextile of the radix lot of Debilitated Bodies and into a trine with the directed 3rd (relatives, travel)
• the directed lot of Journeys is changing degree, moving into a semi-sextile of radix Uranus
• in the maiora esse, the lot of the Destroyer is critical
• in the minora esse, the 11th, Neptune, Pluto, and the lot of Enemies are all critical along with Saturn (LoY)

Event: July 3, 1850 – Former PM and friend, Robert Peel, dies
On July 3, 1850 the former PM, Robert Peel, whom Victoria considered a friend, died when he fell off his horse. The Age Arc was 31º 7'.

• directed Venus, general significator of friends, is critical but not involved in a directed aspect
• the directed lot of Death is critical and ruled by Venus but not involved in a directed aspect
• the directed 12th is changing degree, moving from a sextile of Mars (ruler of the profected 11th) to conjunct radix Jupiter (ruler of the radix 8th, profected 12th) while directed Mars is trine the radix lot of death
• in the maiora esse, the 11th, 8th, and Pluto are all critical as is Venus
• in the minora esse, the 11th is conjunct the radix 12th and Mars, ruler of the profected 11th is in a mitigated sextile (trine) with radix Pluto and inconjunct radix Neptune